Composition:

Sodium salycylate, Sodium ascorbate

Indications:

• Treatment of inflammation in combination with concurrent antiinfective therapy.
• Supportive treatment of pyrexia in acute respiratory disease in combination with appropriate (e.g. anti-infective) therapy if necessary.
• To improve endurance in animals in case of stressful conditions.

Principles of action:

Sodium salicylate is a NSAID and has an anti-inflammatory, analgesic and antipyretic effect. The mode of action is based on inhibition of the enzyme cyclooxygenase, resulting in decreased production of prostaglandin (inflammation mediators). Oral administration is rapidly absorbed and sodium salicylate distributes very well to the various tissues.

Vitamin C has a very complex functional role in the body. Although the respond of susceptible organisms to a deficiency and replenishment of vitamin C has been carefully observed and the biochemicals reactions in which vitamin C may participate have been identified, no unequivocal mechanisms of action have been established. Normal development of cartilage, bone, and dentine is dependent upon an adequate supply of vitamin C. Additionally, the basement membrane lining the capillaries, the intracellular cement holding together the endothelial cells, and the scar tissue responsible for wound healing all require the presence of vitamin C for their formation and maintenance.